Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370913 | 0.91 | NPY5R (0.57) | NPY5RCYP11B2CYP11B1KDM4ENPC1 | |
| SCHEMBL7371445 | 0.85 | NPY5R (0.67) | NPY5RNPSR1ALDH1A1SMPD3L3MBTL1 | |
| SCHEMBL27674585 | 0.83 | NPY5R (0.67) | NPY5RCYP11B2CYP11B1NPC1CYP17A1 | |
| SCHEMBL28763036 | 0.83 | NPY5R (0.74) | NPY5RCYP11B2CYP11B1KDM4ENPC1 | |
| SCHEMBL7370879 | 0.82 | NPY5R (0.59) | NPY5RCYP11B2CYP11B1NPC1CYP17A1 | |
| SCHEMBL7369602 | 0.81 | NPY5R (0.56) | NPY5RCYP11B2CYP11B1CYP19A1CYP3A4 | |
| SCHEMBL7372225 | 0.81 | NPY5R (0.62) | NPY5RCYP11B2CYP11B1CYP17A1CYP19A1 | |
| SCHEMBL7368078 | 0.80 | NPY5R (0.53) | NPY5RCYP11B2CYP11B1CYP17A1CYP19A1 | |
| SCHEMBL7372369 | 0.80 | NPY5R (0.59) | NPY5RKDM4EALDH1A1HPGDSMPD3 | |
| SCHEMBL7371145 | 0.80 | NPY5R (0.65) | NPY5RKDM4ENPSR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |