Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370913 | 0.87 | NPY5R (0.57) | NPY5RSMPD3CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7372225 | 0.86 | NPY5R (0.62) | NPY5RMKNK1MKNK2SMPD3CYP19A1 | |
| SCHEMBL7371445 | 0.84 | NPY5R (0.67) | NPY5RSMPD3MAPTHTTPDGFRB | |
| SCHEMBL7377111 | 0.84 | NPY5R (0.54) | NPY5RMKNK1MKNK2SMPD3CYP19A1 | |
| SCHEMBL7368078 | 0.84 | NPY5R (0.53) | NPY5RMKNK1MKNK2SMPD3CYP19A1 | |
| SCHEMBL7370879 | 0.81 | NPY5R (0.59) | NPY5RMKNK1MKNK2SMPD3MAPT | |
| SCHEMBL7365692 | 0.81 | NPY5R (0.57) | NPY5RSMPD3CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7370252 | 0.80 | ALDH1A1 (0.53) | NPY5RMKNK1MKNK2SMPD3MAPT | |
| SCHEMBL21076869 | 0.80 | MKNK1 (0.66) | MKNK1MKNK2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7372369 | 0.79 | NPY5R (0.59) | NPY5RSMPD3MAPTPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |