Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.59 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372369 | 0.91 | NPY5R (0.59) | NPY5RTP53MAPTSMPD3PDGFRB | |
| SCHEMBL7371445 | 0.84 | NPY5R (0.67) | NPY5RMAPTSMPD3PDGFRBPDGFRA | |
| SCHEMBL7371145 | 0.83 | NPY5R (0.65) | NPY5RTP53MAPTSMPD3PDGFRB | |
| SCHEMBL7365692 | 0.82 | NPY5R (0.57) | NPY5RSMPD3CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL7370913 | 0.82 | NPY5R (0.57) | NPY5RSMPD3CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL7369602 | 0.81 | NPY5R (0.56) | NPY5RMAPTSMPD3CYP11B1CYP11B2 | |
| SCHEMBL7372225 | 0.81 | NPY5R (0.62) | NPY5RSMPD3CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL7377111 | 0.80 | NPY5R (0.54) | NPY5RSMPD3CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL27503313 | 0.79 | CYP17A1 (0.60) | CYP17A1CYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL7368078 | 0.77 | NPY5R (0.53) | NPY5RSMPD3CYP17A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |