Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | FPR2 | P25090 | 6/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23129556 | 0.90 | FPR2 (0.67) | MMEACEFPR2 | |
| SCHEMBL4456099 | 0.85 | ERCC1 (0.50) | MMELMNA | |
| SCHEMBL4456109 | 0.85 | ERCC1 (0.50) | MMELMNA | |
| SCHEMBL7365183 | 0.84 | TACR1 (0.60) | ACE | |
| SCHEMBL21777173 | 0.83 | MME (0.61) | MMEACENPSR1FPR2NAALAD2 | |
| SCHEMBL7370980 | 0.83 | TP53 (0.56) | — | |
| SCHEMBL13358894 | 0.83 | FNTA (0.51) | MMEACELMNA | |
| SCHEMBL19974071 | 0.83 | L3MBTL1 (0.60) | MMEACENPSR1NAALAD2ECE1 | |
| SCHEMBL13358896 | 0.83 | FNTA (0.51) | MMEACELMNA | |
| SCHEMBL14456823 | 0.83 | L3MBTL1 (0.60) | MMEACENPSR1NAALAD2ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001973-A1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999006433-A1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | claimed |
| EP-1001973-A1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006433-A1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | disclosed |