Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.75 |
| ▸ | SI | P14410 | 2/20 | 0.67 |
| ▸ | MGAM | O43451 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.67 |
| ▸ | KDM5A | P29375 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | CASP7 | P55210 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28251596 | 0.86 | MAOA (0.69) | MAOASIMGAMGAAMGAM2 | |
| SCHEMBL28246374 | 0.86 | MAOA (0.69) | MAOASIMGAMGAAMGAM2 | |
| SCHEMBL29633014 | 0.83 | MAOA (0.69) | MAOASIMGAMGAAMGAM2 | |
| SCHEMBL1445004 | 0.83 | MAOA (0.69) | MAOASIMGAMGAAMGAM2 | |
| SCHEMBL30346292 | 0.83 | MGAM (0.70) | MAOASIMGAMGAAMGAM2 | |
| SCHEMBL28990282 | 0.83 | MGAM (0.70) | MAOASIMGAMGAAMGAM2 | |
| SCHEMBL28019778 | 0.81 | MAOA (0.67) | MAOASIMGAMGAAMGAM2 | |
| SCHEMBL9836078 | 0.81 | MGAM (0.63) | MAOASIMGAMGAAMGAM2 | |
| SCHEMBL12500715 | 0.80 | MAOA (0.64) | MAOASIMGAMGAAMGAM2 | |
| SCHEMBL2314333 | 0.80 | MGAM (1.00) | MAOASIMGAMGAAMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888052-A4 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP (US) | 2002-05-22 | — | — | EP | claimed |
| EP-0888052-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORPORATION (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997034482-A1 | XANTHONE ANALOGS FOR THE TREATMENT OF INFECTIOUS DISEASES | INTERLAB CORP. (US) | 1997-09-25 | — | — | WO | claimed |
| EP-0076582-B1 | NEW POLYESTER COMPOSITIONS; SHAPED ARTICLES OBTAINED FROM THEM AND PROCESSES FOR PREPARING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-18 | — | — | EP | claimed |
| US-4456746-A | ULTRAVIOLET STABLE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-06-26 | — | — | US | claimed |
| EP-0076582-A1 | New polyester compositions; shaped articles obtained from them and processes for preparing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-04-13 | — | — | EP | claimed |
| CN-108567771-A | Application of the 1,3,7- trihydroxies xanthone in terms of cardiovascular drugs, pharmaceutical composition and health food | 莆田学院 | 2018-09-25 | — | — | CN | disclosed |
| CN-107793361-A | A kind of imidazole sulfonic acid ionic liquid compositions and its preparation method and application | 天津农学院 | 2018-03-13 | — | — | CN | disclosed |
| CN-104557892-B | A kind of mangiferin unit point derivative and its production and use | 北京大学 | 2018-01-02 | — | — | CN | disclosed |
| CN-104557892-A | Mangiferin single-site derivative and preparation method and application thereof | UNIV BEIJING | 2015-04-29 | — | — | CN | disclosed |
| CN-102212067-B | Garcinia derivative, method for preparing same and pharmaceutical application thereof | UNIV CHINA PHARMA | 2013-01-30 | — | — | CN | disclosed |
| CN-102212067-A | Garcinia derivative, method for preparing same and pharmaceutical application thereof | UNIV CHINA PHARMA | 2011-10-12 | — | — | CN | disclosed |
| EP-0296625-A2 | Agent for inhibiting binding of 5 alpha -dihydrotestosterone with androgen receptor as well as process for obtaining same | Kabushiki Kaisha Vitamin Kenkyusyo (JP) | 1988-12-28 | — | — | EP | disclosed |
| EP-0076582-B1 | NEW POLYESTER COMPOSITIONS; SHAPED ARTICLES OBTAINED FROM THEM AND PROCESSES FOR PREPARING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-18 | — | — | EP | disclosed |
| US-4456746-A | ULTRAVIOLET STABLE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-06-26 | — | — | US | disclosed |
| EP-0076582-A1 | New polyester compositions; shaped articles obtained from them and processes for preparing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-04-13 | — | — | EP | disclosed |