Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.69 |
| ▸ | KDM5A | P29375 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | MGAM | O43451 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | SI | P14410 | 2/20 | 0.61 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445004 | 1.00 | MAOA (0.69) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL1179868 | 0.85 | MAOA (0.52) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL7365848 | 0.83 | MAOA (0.75) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL30346453 | 0.81 | MAOA (1.00) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL873750 | 0.81 | MAOA (1.00) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL30600021 | 0.81 | MAOA (1.00) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL20346606 | 0.79 | MAOA (0.75) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL7982381 | 0.77 | PTGS2 (0.57) | MAOAKDM5APTGS2GAAKDM4E | |
| 3,4-Dihydroxyxanthone SCHEMBL133422 | 0.77 | PTGS2 (1.00) | MAOAKDM5APTGS2GAAKDM4E | |
| SCHEMBL20346629 | 0.77 | MAOA (0.76) | MAOAKDM5APTGS2MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12275711-B2 | Compounds having excited state intramolecular proton transfer (ESIPT) character for use in treating and/or preventing sunburn and/or preventing U.V. damage | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2025-04-15 | — | — | US | disclosed |
| US-20220144785-A1 | COMPOUNDS HAVING EXCITED STATE INTRAMOLECULAR PROTON TRANSFER (ESIPT) CHARACTER FOR USE IN TREATING AND/OR PREVENTING SUNBURN AND/OR PREVENTING U.V. DAMAGE | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12275711-B2 | Compounds having excited state intramolecular proton transfer (ESIPT) character for use in treating and/or preventing sunburn and/or preventing U.V. damage | NNT, NQO1, SUN2 | MAOA 1964/4885KDM5A 4685/4885PTGS2 1958/4885 |
| US-20220144785-A1 | COMPOUNDS HAVING EXCITED STATE INTRAMOLECULAR PROTON TRANSFER (ESIPT) CHARACTER FOR USE IN TREATING AND/OR PREVENTING SUNBURN AND/OR PREVENTING U.V. DAMAGE | NNT, NQO1, SUN2 | MAOA 1964/4885KDM5A 4685/4885PTGS2 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.