Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.69 |
| ▸ | KDM5A | P29375 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | MGAM | O43451 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | SI | P14410 | 2/20 | 0.61 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633014 | 1.00 | MAOA (0.69) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL1179868 | 0.85 | MAOA (0.52) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL7365848 | 0.83 | MAOA (0.75) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL30346453 | 0.81 | MAOA (1.00) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL873750 | 0.81 | MAOA (1.00) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL30600021 | 0.81 | MAOA (1.00) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL20346606 | 0.79 | MAOA (0.75) | MAOAKDM5APTGS2MGAMGAA | |
| SCHEMBL7982381 | 0.77 | PTGS2 (0.57) | MAOAKDM5APTGS2GAAKDM4E | |
| 3,4-Dihydroxyxanthone SCHEMBL133422 | 0.77 | PTGS2 (1.00) | MAOAKDM5APTGS2GAAKDM4E | |
| SCHEMBL20346629 | 0.77 | MAOA (0.76) | MAOAKDM5APTGS2MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433698-A | Mycobacterium smegmatis bacterial liquid, preparation method thereof and application of mycobacterium smegmatis bacterial liquid in preparation of steroid drug intermediate | 湖北共同药业股份有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-113563403-A | Preparation method of 17 alpha-pregnane acetic acid-4-alkene-3.11.20-trione | 佳尔科生物科技南通有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-109053846-B | Method for preparing ulipristal bisketal acetate | 台州仙琚药业有限公司 | 2020-01-07 | — | — | CN | claimed |
| CN-108997300-A | Fluoro- 1,3- dihydroxy xanthone of 7,8- bis- and its preparation method and application | 莆田学院 | 2018-12-14 | — | — | CN | claimed |
| CN-108752306-A | Fluoro- 1,3- dihydroxy xanthones of 6- and its preparation method and application | 莆田学院 | 2018-11-06 | — | — | CN | claimed |
| CN-105418597-B | 1,3- dihydroxy Xanthone derivative and its purposes in medicine | 成都格瑞赛斯科技有限公司 | 2018-10-16 | — | — | CN | claimed |
| CN-108619132-A | Application of -1,3 dihydroxy xanthone of 7- nitros in terms of preparing antitumor drug | 莆田学院 | 2018-10-09 | — | — | CN | claimed |
| CN-105418597-A | Novel 1,3-dyhydroxylxanthone derivative and application thereof in medicines | CHENGDU GERUI SAISI TECH CO LTD | 2016-03-23 | — | — | CN | claimed |
| EP-0006686-B1 | THE COMPOUND 3,6-BIS(HYDROXYETHOXY)XANTH-9-ONE, LINEAR POLYESTERS, AND SHAPED ARTICLES OBTAINED FROM THE LINEAR POLYESTERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-15 | — | — | EP | claimed |
| CN-113692403-B | Compounds having excited state intramolecular proton transfer (esit) properties for use in the treatment and/or prevention of sunburn and/or prevention of u.v. damage | 约翰内斯堡威特沃特斯兰德大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-115850360-A | Preparation method of deflazacort intermediate | 湖南新合新生物医药有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115433698-A | Mycobacterium smegmatis bacterial liquid, preparation method thereof and application of mycobacterium smegmatis bacterial liquid in preparation of steroid drug intermediate | 湖北共同药业股份有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-113692403-A | Compounds with Excited State Intramolecular Proton Transfer (ESIPT) properties for use in the treatment and/or prevention of sunburn and/or prevention of U.V. damage | 约翰内斯堡威特沃特斯兰德大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-113563403-A | Preparation method of 17 alpha-pregnane acetic acid-4-alkene-3.11.20-trione | 佳尔科生物科技南通有限公司 | 2021-10-29 | — | — | CN | disclosed |
| US-6613797-B2 | New xanthone derivatives useful for treating protozoan diseases | INTERLAB, INC. | 2003-09-02 | — | — | US | disclosed |
| US-20020055644-A1 | Xanthone analogs for treating infectious diseases and complexation of heme and porphyrins | INTERLAB, INC. | 2002-05-09 | — | — | US | disclosed |
| WO-2001041773-A1 | XANTHONE ANALOGS FOR TREATING INFECTIOUS DISEASES AND COMPLEXATION OF HEME AND PORPHYRINS | INTERLAB, INC. (US) | 2001-06-14 | — | — | WO | disclosed |
| WO-1995014689-A1 | FLUORONE AND PYRONIN Y DERIVATIVES | SPECTRA GROUP LIMITED, INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| EP-0296625-A2 | Agent for inhibiting binding of 5 alpha -dihydrotestosterone with androgen receptor as well as process for obtaining same | Kabushiki Kaisha Vitamin Kenkyusyo (JP) | 1988-12-28 | — | — | EP | disclosed |
| EP-0006686-B1 | THE COMPOUND 3,6-BIS(HYDROXYETHOXY)XANTH-9-ONE, LINEAR POLYESTERS, AND SHAPED ARTICLES OBTAINED FROM THE LINEAR POLYESTERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055644-A1 | Xanthone analogs for treating infectious diseases and complexation of heme and porphyrins | XPA, XDH, HMOX1 | MAOA 680/4885KDM5A 2067/4885PTGS2 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.