Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15140944 | 0.77 | CCR3 (0.73) | ACHEBCHECCR3 | |
| SCHEMBL22623844 | 0.74 | ACHE (0.58) | ACHEBCHECCR3 | |
| SCHEMBL7281478 | 0.72 | CCR3 (0.67) | ACHEBCHECCR3 | |
| SCHEMBL3107807 | 0.72 | CCR3 (0.71) | ACHEBCHECCR3 | |
| SCHEMBL7365851 | 0.72 | ACHE (0.62) | ACHE | |
| SCHEMBL3870053 | 0.71 | OPRL1 (0.55) | ACHECCR3 | |
| SCHEMBL24404498 | 0.71 | CCR3 (0.69) | ACHEBCHECCR3 | |
| SCHEMBL4499901 | 0.71 | CCR3 (0.69) | ACHEBCHECCR3 | |
| SCHEMBL4499239 | 0.71 | CCR3 (0.69) | ACHEBCHECCR3 | |
| SCHEMBL1714316 | 0.71 | CCR3 (0.74) | ACHEBCHECCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028157-A1 | NOVEL PIPERIDINE DERIVATIVES 4-SUBSTITUTED BY AN IMIDAZOLIDIN-2-ON-1-YL-ETHYL, TETRAHYDROPYRIMIDIN-2-ON-1-YL-ETHYL AND 1,3-DIAZEPIN-2-ON-1-YL-ETHYL GROUP, AND USE THEREOF AS α2-ADRENERGIC RECEPTOR ANTAGONISTS | PIERRE FABRE MEDICAMENT (FR) | 1997-08-07 | — | — | WO | disclosed |