Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941632 | 0.93 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2PDE10AWDR5 | |
| SCHEMBL7366361 | 0.91 | LMNA (0.44) | ALDH1A1LMNAHPGDMAPK1HTT | |
| SCHEMBL7362803 | 0.90 | PDE5A (0.53) | LMNAHPGDAKR1B1WDR5 | |
| SCHEMBL6941529 | 0.88 | LMNA (0.50) | LMNAHPGDPDE10AAKR1B1WDR5 | |
| SCHEMBL1585401 | 0.87 | PDPK1 (0.50) | PDE10AMAOBAKR1B1WDR5 | |
| SCHEMBL7451626 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDMAPK1HTT | |
| SCHEMBL7509935 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAHPGDMAPK1HTT | |
| SCHEMBL7509941 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAHPGDMAPK1HTT | |
| SCHEMBL31171390 | 0.82 | KMT2A (0.51) | ALDH1A1LMNAHTTSMN1; SMN2AKR1B1 | |
| SCHEMBL6940772 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LMNAHPGDMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |