Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.77 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12558834 | 0.87 | HTR2A (1.00) | HTR2AHTR2CHTR2BHTR6TRPM8 | |
| SCHEMBL29511892 | 0.87 | HTR2A (1.00) | HTR2AHTR2CHTR2BHTR6TRPM8 | |
| SCHEMBL8545281 | 0.84 | HTR2A (0.56) | HTR2AHTR2CHTR2BHTR6KMT2A | |
| SCHEMBL11068196 | 0.82 | HTR2A (0.67) | HTR2AKMT2AMEN1TRPM8MAPT | |
| SCHEMBL11263785 | 0.82 | HTR2A (0.67) | HTR2AKMT2AKDM4ETRPM8MAPT | |
| SCHEMBL23805297 | 0.82 | HTR2A (0.67) | HTR2AHTR6KMT2AKDM4ETRPM8 | |
| SCHEMBL23723405 | 0.82 | HTR2A (0.84) | HTR2AHTR2CHTR2BHTR6KMT2A | |
| SCHEMBL23805249 | 0.82 | HTR2A (0.80) | HTR2AHTR2CHTR2BHTR6TRPM8 | |
| SCHEMBL29361521 | 0.81 | HTR2A (1.00) | HTR2AHTR2CHTR2BHTR6KMT2A | |
| SCHEMBL23805214 | 0.81 | HTR2A (0.79) | HTR2AHTR2CHTR2BHTR6TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8945397-B2 | Methods of inhibiting cyanobacteria growth by administering gramine derivatives | CYANOTROL, LLC (US) | 2015-02-03 | — | — | US | disclosed |
| US-8945397-B2 | Methods of inhibiting cyanobacteria growth by administering gramine derivatives | CYANOTROL, LLC (US) | 2015-02-03 | — | — | US | disclosed |
| US-20140110350-A1 | METHODS OF INHIBITING CYANOBACTERIA GROWTH BY ADMINISTERING GRAMINE DERIVATIVES | SAN FRANCISCO STATE UNIVERSITY (US) | 2014-04-24 | — | — | US | disclosed |
| US-20140110350-A1 | METHODS OF INHIBITING CYANOBACTERIA GROWTH BY ADMINISTERING GRAMINE DERIVATIVES | SAN FRANCISCO STATE UNIVERSITY (US) | 2014-04-24 | — | — | US | disclosed |
| US-5198553-A | PROCESS FOR THE PRODUCTION OF GRAMINE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-03-30 | — | — | US | disclosed |
| WO-1992014709-A2 | CALCIUM CHANNEL ANTAGONISTS AND METHODOLOGY FOR THEIR IDENTIFICATION | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1992-09-03 | — | — | WO | disclosed |