SCHEMBL29511892

SCHEMBL29511892

CN(C)CCc1c[nH]c2cccc(OCc3ccccc3)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 11/20 1.00
HTR6 P50406 2/20 0.68
HTR2C P28335 5/20 0.60
HTR2B P41595 5/20 0.60
HTR1A P08908 4/20 0.60
HTR1D P28221 2/20 0.59
TRPM8 Q7Z2W7 1/20 0.59
DRD1 P21728 1/20 0.56
HTR1B P28222 1/20 0.56
HTR1E P28566 1/20 0.56
ADORA2A P29274 1/20 0.56
ADORA2B P29275 1/20 0.56
HTR7 P34969 1/20 0.56
DRD3 P35462 1/20 0.56
HTR5A P47898 1/20 0.56
SLC6A4 P31645 2/20 0.51
SLC6A2 P23975 1/20 0.48
HTR1F P30939 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12558834 1.00 HTR2A (1.00) HTR2AHTR6HTR2CHTR2BHTR1A
SCHEMBL23723405 0.92 HTR2A (0.84) HTR2AHTR6HTR2CHTR2BHTR1A
SCHEMBL26307651 0.91 HTR2A (0.83) HTR2AHTR6HTR2CHTR2BHTR1A
SCHEMBL26307483 0.90 HTR2A (0.82) HTR2AHTR6HTR2CHTR2BHTR1A
SCHEMBL23805249 0.89 HTR2A (0.80) HTR2AHTR6HTR2CHTR2BHTR1A
SCHEMBL23805277 0.88 HTR2A (0.79) HTR2AHTR6HTR2CHTR2BHTR1A
SCHEMBL23805214 0.88 HTR2A (0.79) HTR2AHTR6HTR2CHTR2BHTR1A
SCHEMBL5770609 0.88 HTR2A (0.78) HTR2AHTR6HTR2CHTR2BHTR1A
Hydrochloric Acid SCHEMBL31390111 0.87 HTR2A (0.77) HTR2AHTR6HTR2CHTR2BHTR1A
SCHEMBL7366247 0.87 HTR2A (0.77) HTR2AHTR6HTR2CHTR2BHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601638-A2 ACETAL, KETAL, AND HEMIAMINAL ANALOGS OF PSILOCIN, PROCESSES FOR THE PREPARATION THEREOF, AND METHODS OF USE ATAI Therapeutics, Inc. (US) 2025-08-20 EP disclosed
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS SYNAPTIVE THERAPEUTICS, LLC 2024-11-07 US disclosed
US-20240182415-A1 ACETAL, KETAL, AND HEMIAMINAL ANALOGS OF PSILOCIN, PROCESSES FOR THE PREPARATION THEREOF, AND METHODS OF USE INVYXIS, INC. 2024-06-06 US disclosed
WO-2024081962-A2 ACETAL, KETAL, AND HEMIAMINAL ANALOGS OF PSILOCIN, PROCESSES FOR THE PREPARATION THEREOF, AND METHODS OF USE INVYXIS, INC. (US) 2024-04-18 WO disclosed
US-20230405026-A1 A Method of Treating Depression by Immune Modulation MYND LIFE SCIENCES INC (CA) 2023-12-21 US disclosed
WO-2022094719-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION PACIFIC MYCO BIOSCIENCES LTD. (CA) 2022-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182415-A1 ACETAL, KETAL, AND HEMIAMINAL ANALOGS OF PSILOCIN, PROCESSES FOR THE PREPARATION THEREOF, AND METHODS OF USE HTR6, HTR2A, HTR2C HTR2A 2/4885HTR6 1/4885HTR2C 3/4885
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS HTR1B, HTR2B, PNMT HTR2A 5/4885HTR6 12/4885HTR2C 4/4885
US-20230405026-A1 A Method of Treating Depression by Immune Modulation ABCF1, ABCF2, ABCB4 HTR2A 377/4885HTR6 549/4885HTR2C 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.