Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370057 | 0.86 | LMNA (0.43) | ABCB1ABCC1ATRMKNK1MKNK2 | |
| SCHEMBL7364571 | 0.85 | ABCB1 (0.42) | ABCB1ABCC1NPC1MAPTKMT2A | |
| SCHEMBL7370123 | 0.81 | ABCB1 (0.49) | ABCB1ABCC1NPC1MAPTKMT2A | |
| SCHEMBL7367135 | 0.81 | CYP11B1 (0.52) | NPC1MAPTKMT2ARAB9AALDH1A1 | |
| SCHEMBL7368423 | 0.80 | CYP19A1 (0.50) | ABCB1ABCC1KMT2ARAB9AALDH1A1 | |
| SCHEMBL7365609 | 0.80 | CYP19A1 (0.45) | MAPTKMT2ARAB9AALDH1A1MEN1 | |
| SCHEMBL7370764 | 0.78 | KDM4E (0.48) | NPC1MAPTRAB9AMKNK1MKNK2 | |
| SCHEMBL7404660 | 0.77 | MAPK1 (0.46) | ABCB1ABCC1NPC1MAPTKMT2A | |
| SCHEMBL7372680 | 0.76 | MAPK1 (0.48) | NPC1MAPTKMT2ARAB9AALDH1A1 | |
| SCHEMBL7366043 | 0.74 | CYP11B1 (0.44) | MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |