Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365609 | 0.92 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2KMT2AALPL | |
| SCHEMBL7370838 | 0.84 | MKNK1 (0.46) | CYP19A1CYP11B1CYP11B2MKNK1MKNK2 | |
| SCHEMBL7364571 | 0.83 | ABCB1 (0.42) | CYP19A1CYP11B1CYP11B2KMT2AMKNK1 | |
| SCHEMBL7370568 | 0.83 | CYP3A4 (0.55) | CYP19A1CYP11B1CYP11B2MKNK1MKNK2 | |
| SCHEMBL7372122 | 0.82 | CYP11B1 (0.46) | CYP19A1CYP11B1CYP11B2KMT2AALPL | |
| SCHEMBL7370764 | 0.82 | KDM4E (0.48) | CYP19A1CYP11B1CYP11B2MKNK1MKNK2 | |
| SCHEMBL7370813 | 0.82 | HTT (0.50) | KMT2ASMN1; SMN2PKMALDH1A1RAB9A | |
| SCHEMBL7371256 | 0.81 | MKNK1 (0.42) | CYP19A1CYP11B1CYP11B2MKNK1MKNK2 | |
| SCHEMBL7373136 | 0.81 | POLB (0.51) | CYP19A1CYP11B1CYP11B2KMT2AMKNK1 | |
| SCHEMBL7372273 | 0.81 | MKNK1 (0.43) | CYP19A1CYP11B1CYP11B2MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |