Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320636 | 0.83 | TPSAB1 (0.40) | HDAC1HDAC8CXCR4SIGMAR1 | |
| SCHEMBL7375088 | 0.82 | TDP1 (0.40) | NAAAFFAR1BCHE | |
| SCHEMBL7279739 | 0.81 | UTS2R (0.43) | PDPK1CYP1A2HCAR2NAAAHRH3 | |
| SCHEMBL7318507 | 0.81 | NPC1 (0.40) | SLC6A3CXCR4SIGMAR1 | |
| SCHEMBL7370031 | 0.80 | GRM2 (0.36) | HDAC1HDAC8DPP4BCHE | |
| SCHEMBL7366403 | 0.74 | NPC1 (0.48) | NAAAHDAC1HDAC8BCHEADRA1A | |
| SCHEMBL7332873 | 0.74 | CYP1A2 (0.66) | PDPK1CYP1A2HCAR2HDAC1HDAC8 | |
| SCHEMBL7370146 | 0.73 | PREP (0.48) | HDAC1HDAC8ADRA1APREPSIGMAR1 | |
| SCHEMBL7374067 | 0.72 | HPGD (0.39) | — | |
| SCHEMBL7370574 | 0.72 | MAPT (0.47) | NAAAHDAC1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461677-B1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-04-16 | — | — | EP | claimed |
| EP-0461677-A1 | Novel thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |