Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3471718 | 0.80 | MET (0.70) | KMT2AMEN1GAAALDH3A1HTT | |
| SCHEMBL3470648 | 0.80 | ALOX5 (0.75) | KMT2AMEN1GAAALDH3A1HTT | |
| SCHEMBL14601697 | 0.79 | ALDH3A1 (0.68) | KMT2AMEN1GAAALDH3A1HTT | |
| SCHEMBL8329551 | 0.77 | ALDH3A1 (1.00) | KMT2AMEN1GAAALDH3A1HTT | |
| SCHEMBL17960655 | 0.75 | HTT (0.69) | KMT2AMEN1GAAALDH3A1HTT | |
| SCHEMBL11610961 | 0.75 | GAA (1.00) | KMT2AMEN1GAAALDH3A1HTT | |
| SCHEMBL422055 | 0.74 | ALDH3A1 (0.77) | KMT2AMEN1GAAALDH3A1HTT | |
| SCHEMBL6643008 | 0.73 | ALDH3A1 (0.63) | KMT2AMEN1GAAALDH3A1HTT | |
| SCHEMBL8599875 | 0.73 | POLB (0.65) | KMT2AMEN1GAAALDH3A1HTT | |
| SCHEMBL12748302 | 0.73 | AKR1C3 (0.61) | KMT2AMEN1L3MBTL1LMNAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |