Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366355 | 1.00 | KDM1A (0.55) | KDM1AALDH1A1KMT2AMEN1HPGD | |
| Hydrochloric Acid SCHEMBL4254703 | 0.98 | KDM1A (0.54) | KDM1AALDH1A1KMT2AMEN1HPGD | |
| Hydrochloric Acid SCHEMBL4254701 | 0.98 | KDM1A (0.54) | KDM1AALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL4259945 | 0.93 | KDM1A (0.51) | KDM1AALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL4259946 | 0.93 | KDM1A (0.51) | KDM1AALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL5054677 | 0.93 | KDM1A (0.51) | KDM1AALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL2826447 | 0.80 | KDM1A (0.51) | KDM1AALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL1380700 | 0.80 | KDM1A (0.51) | KDM1AALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL4260439 | 0.80 | KDM1A (0.51) | KDM1AALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL1380697 | 0.80 | KDM1A (0.51) | KDM1AALDH1A1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889886-A1 | NOVEL PHENANTHRIDINES SUBSTITUTED IN THE 6 POSITION | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997035854-A1 | NOVEL PHENANTHRIDINES SUBSTITUTED IN THE 6 POSITION | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1997-10-02 | — | — | WO | disclosed |