Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.51 |
| ▸ | DPP4 | P27487 | 4/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380697 | 1.00 | KDM1A (0.51) | KDM1ADPP4NR3C1PDE4BPDE4A | |
| SCHEMBL4260439 | 1.00 | KDM1A (0.51) | KDM1ADPP4NR3C1PDE4BPDE4A | |
| SCHEMBL1380700 | 1.00 | KDM1A (0.51) | KDM1ADPP4NR3C1PDE4BPDE4A | |
| SCHEMBL4259946 | 0.88 | KDM1A (0.51) | KDM1ADPP4PDE4BPDE4APDE4C | |
| SCHEMBL4259945 | 0.88 | KDM1A (0.51) | KDM1ADPP4PDE4BPDE4APDE4C | |
| SCHEMBL5054677 | 0.88 | KDM1A (0.51) | KDM1ADPP4PDE4BPDE4APDE4C | |
| SCHEMBL5190710 | 0.87 | KDM1A (0.47) | KDM1ADPP4PDE4BPDE4APDE4C | |
| SCHEMBL5056432 | 0.87 | KDM1A (0.47) | KDM1ADPP4PDE4BPDE4APDE4C | |
| SCHEMBL5334911 | 0.86 | CA2 (0.51) | KDM1ANR3C1ALDH1A1GAA | |
| SCHEMBL5334908 | 0.86 | CA2 (0.51) | KDM1ANR3C1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846390-B1 | NOVEL 6-PYRIDYLPHENANTHRIDINES | NYCOMED GMBH (DE) | 2010-03-17 | — | — | EP | disclosed |
| US-20080214536-A1 | Amido-Substituted 6-Phenylphenanthridines | NYCOMED GMBH (DE) | 2008-09-04 | — | — | US | disclosed |
| US-20080119505-A1 | Novel 6-Pyridylphenanthridines | ALTANA PHARMA AG (DE) | 2008-05-22 | — | — | US | disclosed |
| EP-1858880-A1 | AMIDO-SUBSTITUTED 6-PHENYLPHENANTHRIDINES | Nycomed GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| EP-1846390-A1 | NOVEL 6-PYRIDYLPHENANTHRIDINES | Nycomed GmbH (DE) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006095009-A1 | AMIDO-SUBSTITUTED 6-PHENYLPHENANTHRIDINES | NYCOMED GMBH (DE) | 2006-09-14 | — | — | WO | disclosed |
| US-20060189645-A1 | Novel 6-phenylphenantridines | ALTANA PHARMA AG (DE) | 2006-08-24 | — | — | US | disclosed |
| US-20060189641-A1 | Novel 6-phenlyphenanthridines | NYCOMED GMBH (DE) | 2006-08-24 | — | — | US | disclosed |
| WO-2006082185-A1 | NOVEL 6-PYRIDYLPHENANTHRIDINES | NYCOMED GMBH (DE) | 2006-08-10 | — | — | WO | disclosed |
| US-20060116518-A1 | Novel phenanthridines | ALTANA PHARMA AG (DE) | 2006-06-01 | — | — | US | disclosed |
| EP-1658271-A1 | NOVEL 6-PHENYLPHENANTHRIDINES | ALTANA Pharma AG (DE) | 2006-05-24 | — | — | EP | disclosed |
| EP-1658270-A1 | NOVEL 6-PHENYLPHENANTRIDINES | ALTANA Pharma AG (DE) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005012253-A1 | NOVEL 6-PHENYLPHENANTHRIDINES | ALTANA PHARMA AG (DE) | 2005-02-10 | — | — | WO | disclosed |
| WO-2005012252-A1 | NOVEL 6-PHENYLPHENANTRIDINES | ALTANA PHARMA AG (DE) | 2005-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119505-A1 | Novel 6-Pyridylphenanthridines | PDE4A, PDE4B, PDE4C | KDM1A 901/4885DPP4 23/4885NR3C1 1049/4885 |
| US-20060189645-A1 | Novel 6-phenylphenantridines | PDE4B, PDE4A, PDE4D | KDM1A 820/4885DPP4 25/4885NR3C1 1416/4885 |
| US-20060189641-A1 | Novel 6-phenlyphenanthridines | PDE4A, PDE4B, PDE4C | KDM1A 808/4885DPP4 28/4885NR3C1 1836/4885 |
| US-20080214536-A1 | Amido-Substituted 6-Phenylphenanthridines | PDE4A, PDE4B, PDE3A | KDM1A 1058/4885DPP4 36/4885NR3C1 2406/4885 |
| US-20060116518-A1 | Novel phenanthridines | PDE4A, PDE4B, PDE3A | KDM1A 253/4885DPP4 29/4885NR3C1 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.