Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.45 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
| ▸ | PRKX | P51817 | 1/20 | 0.45 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.45 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 14/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366989 | 0.79 | F2 (0.55) | F2PRSS1 | |
| SCHEMBL7366988 | 0.79 | F2 (0.55) | F2PRSS1 | |
| SCHEMBL27503830 | 0.70 | KMT2A (0.58) | KDM4EMEN1MAPTKMT2AROCK2 | |
| SCHEMBL23211680 | 0.70 | KDM4E (0.51) | KDM4EMEN1MAPTKMT2AROCK2 | |
| SCHEMBL21410863 | 0.70 | KDM4E (0.51) | KDM4EMEN1MAPTKMT2AROCK2 | |
| SCHEMBL7348151 | 0.69 | MAPK1 (0.58) | KDM4EMEN1MAPTKMT2AROCK2 | |
| SCHEMBL7345520 | 0.69 | MAPK1 (0.58) | KDM4EMEN1MAPTKMT2AROCK2 | |
| SCHEMBL18332505 | 0.66 | MAPK1 (0.54) | KDM4EMEN1MAPTKMT2AROCK2 | |
| SCHEMBL7350419 | 0.66 | MAPK1 (0.54) | KDM4EMEN1MAPTKMT2AROCK2 | |
| SCHEMBL10832584 | 0.66 | MAPK1 (0.54) | KDM4EMEN1MAPTKMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |