Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.56 |
| ▸ | CTSL | P07711 | 4/20 | 0.56 |
| ▸ | CTSS | P25774 | 4/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19485480 | 0.94 | CTSK (0.62) | CTSKCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL9219338 | 0.94 | CTSK (0.62) | CTSKCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL2058584 | 0.92 | CTSK (0.60) | CTSKCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL9995844 | 0.92 | CTSK (0.60) | CTSKCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL15018841 | 0.92 | CTSK (0.60) | CTSKCTSLCTSSCTSBALDH1A1 | |
| Water SCHEMBL15019511 | 0.91 | CTSS (0.62) | CTSKCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL15096394 | 0.91 | P2RX7 (0.58) | CTSKCTSLCTSSCTSBALDH1A1 | |
| Water SCHEMBL15019510 | 0.91 | CTSS (0.62) | CTSKCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL23729806 | 0.91 | CTSS (0.58) | CTSKCTSLCTSSCTSBTACR1 | |
| SCHEMBL5887559 | 0.89 | P2RX7 (0.59) | CTSKCTSLCTSSCTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014706-A1 | CYCLOPENTANE-DERIVED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | PFIZER LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |