Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | BCL2 | P10415 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | YAP1 | P46937 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2891538 | 0.88 | PTPN1 (0.73) | PTPN1BCL2ITGB3ITGA2BPPARG | |
| SCHEMBL193474 | 0.88 | PTPN1 (0.73) | PTPN1BCL2ITGB3ITGA2BPPARG | |
| SCHEMBL193473 | 0.88 | PTPN1 (0.73) | PTPN1BCL2ITGB3ITGA2BPPARG | |
| SCHEMBL10421039 | 0.84 | PTPN1 (0.59) | PTPN1BCL2ITGB3ITGA2BGPR132 | |
| SCHEMBL792956 | 0.84 | BCL2 (0.64) | PTPN1BCL2ITGB3ITGA2BPPARG | |
| SCHEMBL28267499 | 0.84 | PTPN1 (0.77) | PTPN1BCL2ITGB3ITGA2BPPARG | |
| SCHEMBL28267496 | 0.84 | PTPN1 (0.77) | PTPN1BCL2ITGB3ITGA2BPPARG | |
| SCHEMBL793015 | 0.82 | BCL2 (0.62) | PTPN1BCL2ITGB3ITGA2BPPARG | |
| SCHEMBL7443966 | 0.82 | PTPN1 (0.61) | PTPN1BCL2ITGB3ITGA2BPPARG | |
| SCHEMBL7366740 | 0.82 | PSMB1 (0.62) | PTPN1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217286-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1987-04-08 | — | — | EP | disclosed |