Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 11/20 | 0.62 |
| ▸ | PSMB5 | P28074 | 11/20 | 0.62 |
| ▸ | PSMB9 | P28065 | 10/20 | 0.62 |
| ▸ | PSMB8 | P28062 | 10/20 | 0.62 |
| ▸ | PSMB10 | P40306 | 5/20 | 0.62 |
| ▸ | PSMB2 | P49721 | 5/20 | 0.62 |
| ▸ | BCL2 | P10415 | 1/20 | 0.61 |
| ▸ | CTSS | P25774 | 4/20 | 0.58 |
| ▸ | CTSK | P43235 | 3/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5833941 | 0.88 | BCL2 (0.60) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL22163625 | 0.86 | PSMB1 (0.58) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL992881 | 0.86 | PSMB1 (0.58) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL993498 | 0.85 | CTSS (0.59) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL12706406 | 0.85 | BCL2 (0.66) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL3383006 | 0.85 | CTSS (0.77) | CTSSCTSKCTSLCTSB | |
| SCHEMBL19982258 | 0.84 | CTSS (0.65) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL12706400 | 0.84 | BCL2 (0.65) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL7283532 | 0.84 | MMP9 (0.69) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL7283537 | 0.84 | MMP9 (0.69) | PSMB1PSMB5PSMB9PSMB8PSMB10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217286-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1987-04-08 | — | — | EP | disclosed |