Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8250956 | 0.87 | MAPK1 (0.53) | HPGDALDH1A1NPSR1MAPTLMNA | |
| SCHEMBL8133261 | 0.84 | HTR1A (0.54) | ALDH1A1MAPTLMNACYP2C19HSD17B10 | |
| Hydrochloric Acid SCHEMBL7365760 | 0.83 | MAPK1 (0.39) | HPGDALDH1A1NPSR1MAPTLMNA | |
| SCHEMBL12814058 | 0.81 | NPSR1 (0.58) | ALDH1A1NPSR1MAPTGAAKDM4E | |
| SCHEMBL7369393 | 0.81 | ADRB1 (0.51) | HPGDALDH1A1NPSR1MAPTGAA | |
| SCHEMBL7368853 | 0.81 | ADRB1 (0.55) | ALDH1A1NPSR1MAPTCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL12814057 | 0.80 | NPSR1 (0.57) | ALDH1A1NPSR1MAPTGAAKDM4E | |
| SCHEMBL22542315 | 0.75 | HPGD (0.59) | HPGDALDH1A1NPSR1MAPTLMNA | |
| Trifluoroacetic Acid SCHEMBL7358937 | 0.74 | ATM (0.48) | HPGDALDH1A1NPSR1MAPTTSHR | |
| SCHEMBL14039382 | 0.74 | FGFR3 (0.49) | ALDH1A1NPSR1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |