Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368853 | 0.92 | ADRB1 (0.55) | ATMADRB1PPARGPPARAALDH1A1 | |
| SCHEMBL7369393 | 0.81 | ADRB1 (0.51) | ATMADRB1PPARGPPARAALDH1A1 | |
| SCHEMBL12814058 | 0.79 | NPSR1 (0.58) | ATMADRB1ALDH1A1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL12814057 | 0.78 | NPSR1 (0.57) | ATMADRB1ALDH1A1HTR3EHTR3B | |
| Trifluoroacetic Acid SCHEMBL27402987 | 0.77 | ALDH1A1 (0.56) | ATMPPARGPPARAALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7358451 | 0.77 | MAPT (0.53) | ADRB1ALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL6922833 | 0.76 | ADRB1 (0.69) | ADRB1ALDH1A1HTR3EHTR3BHTR1D | |
| SCHEMBL8250956 | 0.76 | MAPK1 (0.53) | ATMALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL7364473 | 0.75 | GPR119 (0.53) | ATMPPARGPPARAENPP2ALDH1A1 | |
| SCHEMBL7366945 | 0.74 | HPGD (0.47) | ATMALDH1A1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0892783-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | Dr. Karl Thomae GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037975-A1 | CARBOXYLIC ACID DERIVATIVES WITH AN AGGREGATION-INHIBITING ACTION | DR. KARL THOMAE GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |