Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25426510 | 0.87 | ALDH1A1 (0.54) | CYP2C9CYP2C19CYP1A2ALDH1A1MAPK1 | |
| SCHEMBL7366693 | 0.81 | TSHR (0.51) | POLBCYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL29010221 | 0.79 | CYP46A1 (0.54) | CYP2C9CYP2C19CYP46A1NPSR1CYP2D6 | |
| SCHEMBL6286261 | 0.79 | HDAC6 (0.54) | POLBCTSLCTSBCYP2C9CYP2C19 | |
| SCHEMBL23291465 | 0.78 | POLB (0.48) | POLBCTSLCTSBCYP2C9CYP2C19 | |
| SCHEMBL23291427 | 0.78 | PRMT5 (0.48) | POLBCYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL7745615 | 0.77 | KMT2A (0.52) | POLBCYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL3491164 | 0.77 | ALDH1A1 (0.44) | POLBCTSLCTSBCYP2C9CYP2C19 | |
| SCHEMBL21878243 | 0.77 | CTSL (0.48) | CTSLCTSBCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL3490697 | 0.76 | ALDH1A1 (0.45) | CYP2C9CYP2C19CYP1A2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211183-B1 | PIPERAZINE DERIVATIVE ANTICOAGULANTS; ANTIISCHEMIC AGENTS; CARDIOVASCULAR DISORDERS | COR THERAPEUTICS, INC. | 2001-04-03 | — | — | US | disclosed |
| EP-0975625-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046591-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1998-10-22 | — | — | WO | disclosed |