Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745615 | 0.87 | KMT2A (0.52) | TSHRCASP3ALOX15ALDH1A1KMT2A | |
| SCHEMBL7461145 | 0.85 | HDAC6 (0.53) | TSHRCASP3ALOX15ALDH1A1KMT2A | |
| SCHEMBL7737652 | 0.82 | PLA2G10 (0.50) | TSHRALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL25426510 | 0.81 | ALDH1A1 (0.54) | TSHRALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL7367041 | 0.81 | POLB (0.44) | TSHRALDH1A1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL7365707 | 0.81 | KMT2A (0.66) | TSHRALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL12957540 | 0.79 | KMT2A (0.54) | TSHRKMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL1488276 | 0.78 | L3MBTL1 (0.56) | TSHRKMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL3491164 | 0.76 | ALDH1A1 (0.44) | TSHRALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL7368700 | 0.76 | RAB9A (0.48) | TSHRALDH1A1KMT2AMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211183-B1 | PIPERAZINE DERIVATIVE ANTICOAGULANTS; ANTIISCHEMIC AGENTS; CARDIOVASCULAR DISORDERS | COR THERAPEUTICS, INC. | 2001-04-03 | — | — | US | disclosed |
| EP-0975625-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046591-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1998-10-22 | — | — | WO | disclosed |