Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965911 | 0.88 | TP53 (0.56) | RAB9ACYP1A2ALDH1A1KDM4ENPC1 | |
| SCHEMBL6961250 | 0.87 | ALDH1A1 (0.54) | RAB9ACYP1A2ALDH1A1KDM4ENPC1 | |
| SCHEMBL7372458 | 0.85 | RAB9A (0.57) | RAB9AALDH1A1KDM4ENPC1NPSR1 | |
| SCHEMBL8319324 | 0.85 | RAB9A (0.64) | RAB9ACYP1A2ALDH1A1KDM4ENPC1 | |
| SCHEMBL7334998 | 0.84 | ALDH1A1 (0.65) | RAB9ACYP1A2ALDH1A1KDM4ENPC1 | |
| SCHEMBL8816442 | 0.84 | RAB9A (0.62) | RAB9ACYP1A2ALDH1A1KDM4ENPC1 | |
| SCHEMBL8318448 | 0.84 | ALDH1A1 (0.56) | RAB9ACYP1A2ALDH1A1KDM4ENPC1 | |
| SCHEMBL27525547 | 0.83 | RAB9A (0.50) | RAB9ACYP1A2ALDH1A1KDM4ENPC1 | |
| SCHEMBL7611583 | 0.81 | RAB9A (0.71) | RAB9ACYP1A2ALDH1A1KDM4ENPC1 | |
| SCHEMBL8317200 | 0.81 | RAB9A (0.54) | RAB9ACYP1A2ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |