Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897711 | 0.86 | MEN1 (0.64) | KMT2AMEN1LMNANPY1RADRB2 | |
| SCHEMBL4897725 | 0.86 | MEN1 (0.64) | KMT2AMEN1LMNANPY1RADRB2 | |
| SCHEMBL25053044 | 0.83 | ADRB1 (0.69) | KMT2AMEN1LMNANPY1RADRB2 | |
| SCHEMBL20854554 | 0.82 | DRD4 (0.67) | KMT2AMEN1LMNACYP2D6MAPT | |
| SCHEMBL5799574 | 0.81 | LMNA (0.61) | KMT2AMEN1LMNANPY1RADRB2 | |
| SCHEMBL5814362 | 0.81 | LMNA (0.61) | KMT2AMEN1LMNANPY1RADRB2 | |
| SCHEMBL24225590 | 0.80 | MEN1 (0.58) | KMT2AMEN1LMNAADRB2ADRB1 | |
| SCHEMBL29045817 | 0.80 | KMT2A (0.75) | KMT2AMEN1LMNANPY1RMAPT | |
| SCHEMBL20883491 | 0.79 | LMNA (0.64) | KMT2AMEN1LMNANPY1RADRB2 | |
| Hydrochloric Acid SCHEMBL5144170 | 0.77 | KMT2A (0.63) | KMT2AMEN1LMNANPY1RADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002463-A1 | ANTIHYPERTENSIVE 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-03 | — | — | WO | disclosed |