Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.55 |
| ▸ | DPP4 | P27487 | 2/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5814362 | 1.00 | LMNA (0.61) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4894557 | 0.85 | MEN1 (0.58) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4894572 | 0.85 | MEN1 (0.58) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4584979 | 0.85 | ADRB2 (0.54) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL25053044 | 0.85 | ADRB1 (0.69) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20854554 | 0.84 | DRD4 (0.67) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL24225590 | 0.81 | MEN1 (0.58) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7367153 | 0.81 | KMT2A (0.67) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20883491 | 0.81 | LMNA (0.64) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20883380 | 0.79 | LMNA (0.57) | LMNAMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060122-A9 | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST BETA-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE | ARTESIAN THERAPEUTICS INC (US) | 2006-08-17 | — | — | WO | disclosed |