Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 6/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367157 | 1.00 | NAALAD2 (0.58) | NAALAD2FOLH1L3MBTL1FPR2MME | |
| SCHEMBL7370001 | 0.85 | NPC1 (0.51) | MMEMEN1KMT2A | |
| SCHEMBL7369997 | 0.85 | NPC1 (0.51) | MMEMEN1KMT2A | |
| SCHEMBL18180178 | 0.83 | NAALAD2 (0.78) | NAALAD2FOLH1L3MBTL1FPR2MME | |
| SCHEMBL19969196 | 0.83 | NAALAD2 (0.78) | NAALAD2FOLH1L3MBTL1FPR2MME | |
| SCHEMBL7367862 | 0.81 | MME (0.54) | MMEALDH1A1MEN1KMT2A | |
| SCHEMBL4316009 | 0.79 | NAALAD2 (0.71) | NAALAD2FOLH1L3MBTL1FPR2MME | |
| SCHEMBL4314395 | 0.79 | NAALAD2 (0.71) | NAALAD2FOLH1L3MBTL1FPR2MME | |
| SCHEMBL10909093 | 0.79 | NAALAD2 (0.71) | NAALAD2FOLH1L3MBTL1FPR2MME | |
| SCHEMBL7366443 | 0.78 | MME (0.51) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | claimed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | claimed |
| EP-0117429-B1 | PHOSPHOROUS CONTAINING COMPOUNDS AS INHIBITORS OF ENKEPHALINASES | SCHERING CORPORATION (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0117429-A1 | Phosphorous containing compounds as inhibitors of enkephalinases | SCHERING CORPORATION (US) | 1984-09-05 | — | — | EP | disclosed |