Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
| ▸ | SORD | Q00796 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344373 | 0.89 | RIPK1 (0.38) | GPR119RIPK1PARP1GPBAR1CYP2D6 | |
| SCHEMBL7343911 | 0.88 | HRH3 (0.44) | HRH3 | |
| SCHEMBL7349534 | 0.83 | HRH3 (0.35) | HRH3 | |
| SCHEMBL8551353 | 0.79 | HTR2B (0.42) | GPR119HRH3RIPK1PARP1GPBAR1 | |
| SCHEMBL7367199 | 0.76 | PARP1 (0.38) | HRH3PARP1 | |
| SCHEMBL7344262 | 0.74 | HRH3 (0.40) | HRH3 | |
| SCHEMBL7342864 | 0.74 | PARP1 (0.40) | HRH3PARP1 | |
| SCHEMBL7375522 | 0.74 | GPR119 (0.36) | GPR119HRH3RIPK1PARP1GPBAR1 | |
| SCHEMBL7376503 | 0.72 | OGA (0.41) | HRH3 | |
| SCHEMBL7349527 | 0.71 | F10 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891359-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036899-A1 | NOVEL OXAZOLIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-09 | — | — | WO | disclosed |