Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368100 | 0.85 | HTR2A (0.35) | HTR2ATAAR1HSD17B10 | |
| SCHEMBL7114175 | 0.79 | ALDH1A1 (0.46) | — | |
| SCHEMBL31589433 | 0.74 | KDM4E (0.45) | HSD17B10 | |
| SCHEMBL19237538 | 0.72 | TAAR1 (0.43) | HTR2ATAAR1 | |
| SCHEMBL282797 | 0.71 | HTR2A (0.43) | HTR2ATAAR1HSD17B10 | |
| SCHEMBL7121462 | 0.71 | AKR1B1 (0.39) | HTR2AHSD17B10 | |
| SCHEMBL11974262 | 0.69 | ALDH1A1 (0.42) | HSD17B10 | |
| SCHEMBL7368018 | 0.69 | BCL2 (0.37) | NR3C1PGRNR3C2HSD17B10 | |
| SCHEMBL2629462 | 0.68 | ALDH1A1 (0.48) | — | |
| SCHEMBL12326164 | 0.68 | ALDH1A1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991618-A4 | SELECTIVE THYROID HORMONE ANALOGS | UNIV CALIFORNIA (US) | 2000-09-27 | — | — | EP | disclosed |
| EP-0991618-A1 | SELECTIVE THYROID HORMONE ANALOGS | The Regents of the University of California (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057919-A1 | SELECTIVE THYROID HORMONE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-12-23 | — | — | WO | disclosed |