Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367350 | 0.85 | HTR2A (0.37) | HTR2ATAAR1HSD17B10 | |
| SCHEMBL7114175 | 0.73 | ALDH1A1 (0.46) | AKR1B1 | |
| SCHEMBL12226957 | 0.70 | CYP2D6 (0.53) | CYP2D6ADRA1ATAAR1MEN1KMT2A | |
| SCHEMBL282797 | 0.69 | HTR2A (0.43) | HTR2ACYP2D6ADRA1ATAAR1ADRA2A | |
| SCHEMBL1145887 | 0.67 | ADRA1A (0.68) | HTR2ACYP2D6ADRA1ATAAR1HSD17B10 | |
| SCHEMBL48353 | 0.67 | APLNR (0.59) | HTR2ACYP2D6ADRA1ATAAR1MEN1 | |
| SCHEMBL11974262 | 0.66 | ALDH1A1 (0.42) | CYP2D6HSD17B10 | |
| SCHEMBL28928134 | 0.66 | CYP1A2 (0.39) | — | |
| SCHEMBL2629462 | 0.65 | ALDH1A1 (0.48) | KMT2A | |
| SCHEMBL12326164 | 0.65 | ALDH1A1 (0.59) | CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991618-A4 | SELECTIVE THYROID HORMONE ANALOGS | UNIV CALIFORNIA (US) | 2000-09-27 | — | — | EP | disclosed |
| EP-0991618-A1 | SELECTIVE THYROID HORMONE ANALOGS | The Regents of the University of California (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057919-A1 | SELECTIVE THYROID HORMONE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-12-23 | — | — | WO | disclosed |