Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.64 |
| ▸ | ITGAV | P06756 | 16/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541762 | 0.79 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7368808 | 0.78 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL7499918 | 0.78 | ITGB3 (0.85) | ITGB3ITGAVITGA2B | |
| SCHEMBL7497274 | 0.78 | ITGB3 (0.78) | ITGB3ITGAVITGA2B | |
| SCHEMBL7368068 | 0.77 | CDK4 (0.51) | — | |
| SCHEMBL5972553 | 0.75 | ITGB3 (0.68) | ITGB3ITGAVITGA2B | |
| SCHEMBL6677335 | 0.75 | ITGB3 (0.68) | ITGB3ITGAVITGA2B | |
| SCHEMBL6677340 | 0.75 | ITGB3 (0.68) | ITGB3ITGAVITGA2B | |
| Lotrafiban SCHEMBL29596 | 0.75 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| Lotrafiban SCHEMBL6673128 | 0.75 | ITGB3 (1.00) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-5977101-A | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |