Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 17/20 | 0.51 |
| ▸ | CCND1 | P24385 | 17/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367441 | 0.77 | ITGB3 (0.64) | — | |
| SCHEMBL7366389 | 0.75 | TSHR (0.43) | — | |
| SCHEMBL7078805 | 0.75 | TSHR (0.43) | — | |
| SCHEMBL7658169 | 0.74 | ITGB3 (0.56) | — | |
| SCHEMBL6335099 | 0.72 | CDK4 (0.76) | CDK4CCND1NAMPTTRPV1 | |
| SCHEMBL7368305 | 0.71 | ITGB3 (0.60) | — | |
| SCHEMBL13942053 | 0.71 | CDK4 (0.93) | CDK4CCND1NAMPTTRPV1 | |
| SCHEMBL13942052 | 0.71 | CDK4 (0.85) | CDK4CCND1NAMPTTRPV1 | |
| SCHEMBL13942584 | 0.70 | CDK4 (0.88) | CDK4CCND1TRPV1 | |
| SCHEMBL13943092 | 0.70 | CDK4 (0.86) | CDK4CCND1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767792-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-0767792-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000730-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-01-11 | — | — | WO | disclosed |