Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957340 | 0.89 | KDM4E (0.46) | KDM4EPKMGPR119FAAHFPR2 | |
| SCHEMBL7277084 | 0.85 | FAAH (0.46) | KDM4EPKMGPR119FAAHMAPT | |
| SCHEMBL8892804 | 0.80 | KDM4E (0.55) | KDM4EPKMGPR119FAAH | |
| Hydrochloric Acid SCHEMBL8669970 | 0.80 | TP53 (0.45) | KDM4EPKMGPR119MAPTTHRB | |
| SCHEMBL28437919 | 0.79 | NR1H2 (0.43) | KDM4EPKMGPR119FAAHMAPT | |
| SCHEMBL7367257 | 0.79 | KDM4E (0.47) | KDM4EPKMGPR119FAAHMAPT | |
| SCHEMBL9031543 | 0.79 | TP53 (0.46) | KDM4EPKMGPR119MAPTTHRB | |
| SCHEMBL7274902 | 0.79 | ACE (0.49) | KDM4EPKMGPR119FAAHFPR2 | |
| SCHEMBL7274867 | 0.78 | KDM4E (0.45) | KDM4EPKMGPR119FAAHFPR2 | |
| SCHEMBL7395465 | 0.78 | GPR119 (0.48) | KDM4EPKMGPR119FAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211183-B1 | PIPERAZINE DERIVATIVE ANTICOAGULANTS; ANTIISCHEMIC AGENTS; CARDIOVASCULAR DISORDERS | COR THERAPEUTICS, INC. | 2001-04-03 | — | — | US | disclosed |
| EP-0975625-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046591-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1998-10-22 | — | — | WO | disclosed |