Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL189570 | 0.90 | FPR2 (0.51) | KDM4EALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL29056036 | 0.86 | FPR2 (0.50) | KDM4EGPR119HPGDPKMEPHX1 | |
| SCHEMBL7277012 | 0.85 | KDM4E (0.45) | KDM4EALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL26130347 | 0.85 | FPR2 (0.45) | KDM4EALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL26128387 | 0.85 | HPGD (0.51) | KDM4EGPR119HPGDPKMEPHX1 | |
| SCHEMBL7283170 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL16365258 | 0.83 | ADRA1D (0.48) | KDM4EALDH1A1GAASMN1; SMN2HPGD | |
| SCHEMBL7277084 | 0.82 | FAAH (0.46) | KDM4EGPR119FAAHHPGDPKM | |
| SCHEMBL7395465 | 0.82 | GPR119 (0.48) | KDM4EGPR119FAAHPKM | |
| SCHEMBL7274948 | 0.81 | GPR119 (0.40) | KDM4EALDH1A1GAATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4506344-A1 | 1,4-DIHETEROCYCLIC SUBSTITUTED AROMATIC RING OR AROMATIC HETEROCYCLIC COMPOUND AND USE THEREOF | Bebetter Med Inc. (CN) | 2025-02-12 | — | — | EP | disclosed |
| US-20250034116-A1 | 1,4-DIHETEROCYCLIC SUBSTITUTED AROMATIC RING OR AROMATIC HETEROCYCLIC COMPOUND AND USE THEREOF | BEBETTER MED INC. (CN) | 2025-01-30 | — | — | US | disclosed |
| CN-116615417-B | 1, 4-Diheterocyclic group substituted aromatic ring or aromatic heterocyclic compound and application thereof | 广州必贝特医药股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-2023185821-A1 | 1,4-DIHETEROCYCLIC SUBSTITUTED AROMATIC RING OR AROMATIC HETEROCYCLIC COMPOUND AND USE THEREOF | 广州必贝特医药股份有限公司 | 2023-10-05 | — | — | WO | disclosed |
| CN-116615417-A | 1, 4-diheterocycle substituted aromatic ring or aromatic heterocyclic compound and application thereof | 广州必贝特医药股份有限公司 | 2023-08-18 | — | — | CN | disclosed |
| WO-1997043292-A1 | NEW THIAZOLOPYRIDINES | KLINGE PHARMA GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |
| CN-1067883-A | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1993-01-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034116-A1 | 1,4-DIHETEROCYCLIC SUBSTITUTED AROMATIC RING OR AROMATIC HETEROCYCLIC COMPOUND AND USE THEREOF | CYP46A1, CYP4A22, CYP2C19 | KDM4E 749/4885ALDH1A1 233/4885GAA 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.