Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367701 | 0.91 | ADORA1 (0.42) | NSD3ADORA1DPP4KCNH2IGF1R | |
| SCHEMBL7371146 | 0.90 | ADORA1 (0.41) | NSD3ADORA1DPP4KCNH2IGF1R | |
| SCHEMBL7367704 | 0.88 | ADORA1 (0.40) | NSD3ADORA1DPP4KCNH2IGF1R | |
| SCHEMBL7486447 | 0.88 | NSD3 (0.52) | NSD3ADORA1DPP4IGF1RDPP8 | |
| Hydrochloric Acid SCHEMBL7485696 | 0.87 | NSD3 (0.51) | NSD3ADORA1DPP4IGF1RDPP8 | |
| SCHEMBL7365777 | 0.85 | ADORA1 (0.39) | NSD3ADORA1DPP4KCNH2IGF1R | |
| SCHEMBL7365779 | 0.85 | ADORA1 (0.39) | NSD3ADORA1DPP4KCNH2IGF1R | |
| SCHEMBL7492330 | 0.82 | ADORA1 (0.50) | NSD3ADORA1PIM1DPP4IGF1R | |
| Hydrochloric Acid SCHEMBL7495672 | 0.81 | ADORA1 (0.49) | NSD3ADORA1PIM1DPP4IGF1R | |
| SCHEMBL7373031 | 0.78 | ADORA1 (0.48) | ADORA1IGF1RALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244669-A1 | PYRAZOLOPYRAZINES AND THEIR USE AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001040230-A1 | PYRAZOLOPYRAZINES AND THEIR USE AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-07 | — | — | WO | disclosed |