Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361782 | 0.81 | ACE (0.59) | ACEACE2 | |
| SCHEMBL7361785 | 0.81 | ACE (0.59) | ACEACE2 | |
| SCHEMBL7330602 | 0.77 | ACE (0.66) | ACEACE2 | |
| SCHEMBL10942007 | 0.76 | ACE (0.58) | ACEACE2 | |
| SCHEMBL10847172 | 0.75 | ACE (0.51) | ACEACE2 | |
| SCHEMBL7365238 | 0.75 | ACE (0.54) | ACEACE2 | |
| SCHEMBL7365239 | 0.75 | ACE (0.54) | ACEACE2 | |
| SCHEMBL10679400 | 0.74 | ACE (0.66) | ACEACE2 | |
| SCHEMBL4955191 | 0.74 | DPP8 (0.71) | ACEACE2 | |
| SCHEMBL9040814 | 0.74 | DPP8 (0.71) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132304-A2 | Hydroxy substituted peptide compounds | E.R. Squibb & Sons, Inc. (US) | 1985-01-30 | — | — | EP | disclosed |