Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7364182 | 0.99 | HTR3A (0.55) | HTR3AMEN1KMT2AHTR4 | |
| SCHEMBL7360723 | 0.96 | HTR3A (0.58) | HTR3AMEN1KMT2AHTR4 | |
| SCHEMBL7365435 | 0.77 | HTR3A (0.56) | HTR3AMEN1KMT2A | |
| SCHEMBL7360573 | 0.73 | HTR3A (0.77) | HTR3A | |
| SCHEMBL7362682 | 0.72 | HTR3A (1.00) | HTR3A | |
| SCHEMBL1761694 | 0.71 | HTR3A (0.62) | HTR3A | |
| SCHEMBL7416813 | 0.71 | HTR3A (0.52) | HTR3AMEN1KMT2AHTR4 | |
| SCHEMBL7414248 | 0.71 | HTR3A (0.52) | HTR3AMEN1KMT2AHTR4 | |
| Hydrochloric Acid SCHEMBL7368996 | 0.71 | HTR3A (0.54) | HTR3A | |
| SCHEMBL1006850 | 0.70 | HTR3A (0.58) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530353-A1 | NEW IMIDAZOPYRIDINES AS SEROTONERGIC 5-HT 3? ANTAGONISTS | G.D. SEARLE & CO. (US) | 1993-03-10 | — | — | EP | claimed |
| WO-1992015593-A1 | NEW IMIDAZOPYRIDINES AS SEROTONERGIC 5-HT3 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1992-09-17 | — | — | WO | claimed |