Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 1.00 |
| ▸ | MMP3 | P08254 | 10/20 | 1.00 |
| ▸ | MMP8 | P22894 | 4/20 | 1.00 |
| ▸ | MMP9 | P14780 | 3/20 | 1.00 |
| ▸ | MMP7 | P09237 | 2/20 | 1.00 |
| ▸ | MMP2 | P08253 | 2/20 | 1.00 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367842 | 1.00 | MMP1 (1.00) | MMP1MMP3MMP8MMP9MMP7 | |
| SCHEMBL7367838 | 1.00 | MMP1 (1.00) | MMP1MMP3MMP8MMP9MMP7 | |
| SCHEMBL7708694 | 1.00 | MMP1 (1.00) | MMP1MMP3MMP8MMP9MMP7 | |
| SCHEMBL7456228 | 0.90 | MMP1 (0.81) | MMP1MMP3MMP8MMP9MMP7 | |
| SCHEMBL7410018 | 0.90 | MMP1 (0.81) | MMP1MMP3MMP8MMP9MMP7 | |
| SCHEMBL7410020 | 0.90 | MMP1 (0.81) | MMP1MMP3MMP8MMP9MMP7 | |
| SCHEMBL7360058 | 0.90 | MMP1 (1.00) | MMP1MMP3MMP8MMP9MMP7 | |
| SCHEMBL7360055 | 0.90 | MMP1 (1.00) | MMP1MMP3MMP8MMP9MMP7 | |
| SCHEMBL7408812 | 0.88 | MMP1 (0.79) | MMP1MMP3MMP8MMP9MMP7 | |
| SCHEMBL7409487 | 0.88 | MMP1 (0.79) | MMP1MMP3MMP8MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925303-B1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | PROCTER & GAMBLE (US) | 2002-10-23 | — | — | EP | claimed |
| EP-0925303-A1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-30 | — | — | EP | claimed |
| WO-1998008853-A9 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | — | 1998-08-06 | — | — | WO | claimed |
| WO-1998008853-A1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | claimed |
| EP-0925303-B1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | PROCTER & GAMBLE (US) | 2002-10-23 | — | — | EP | disclosed |
| EP-0925303-A1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998008853-A9 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | — | 1998-08-06 | — | — | WO | disclosed |
| WO-1998008853-A1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |