Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.79 |
| ▸ | MMP3 | P08254 | 10/20 | 0.79 |
| ▸ | MMP7 | P09237 | 2/20 | 0.79 |
| ▸ | MMP9 | P14780 | 2/20 | 0.79 |
| ▸ | MMP2 | P08253 | 1/20 | 0.79 |
| ▸ | MMP8 | P22894 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408812 | 1.00 | MMP1 (0.79) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7365090 | 0.88 | MMP1 (0.74) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7367840 | 0.88 | MMP1 (1.00) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7365086 | 0.88 | MMP1 (0.74) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7708694 | 0.88 | MMP1 (1.00) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7367838 | 0.88 | MMP1 (1.00) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7367842 | 0.88 | MMP1 (1.00) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7400355 | 0.84 | MMP1 (0.65) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7439641 | 0.83 | MMP1 (0.63) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7367886 | 0.83 | MMP1 (0.73) | MMP1MMP3MMP7MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008853-A9 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | — | 1998-08-06 | — | — | WO | disclosed |