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Sugi Predict / Compounds / SCHEMBL7708694

SCHEMBL7708694

SCHEMBL7708694

CC(C)C[C@H](C(=O)NO)N(Cc1ccccc1)[P@@](C)(=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MMP1 P03956 11/20 1.00
▸ MMP3 P08254 10/20 1.00
▸ MMP8 P22894 4/20 1.00
▸ MMP9 P14780 3/20 1.00
▸ MMP7 P09237 2/20 1.00
▸ MMP2 P08253 2/20 1.00
▸ CA1 P00915 1/20 0.50
▸ CA2 P00918 1/20 0.50
▸ MMP13 P45452 1/20 0.50
▸ ANPEP P15144 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7367840 1.00 MMP1 (1.00) MMP1MMP3MMP8MMP9MMP7
SCHEMBL7367842 1.00 MMP1 (1.00) MMP1MMP3MMP8MMP9MMP7
SCHEMBL7367838 1.00 MMP1 (1.00) MMP1MMP3MMP8MMP9MMP7
SCHEMBL7456228 0.90 MMP1 (0.81) MMP1MMP3MMP8MMP9MMP7
SCHEMBL7410018 0.90 MMP1 (0.81) MMP1MMP3MMP8MMP9MMP7
SCHEMBL7410020 0.90 MMP1 (0.81) MMP1MMP3MMP8MMP9MMP7
SCHEMBL7360058 0.90 MMP1 (1.00) MMP1MMP3MMP8MMP9MMP7
SCHEMBL7360055 0.90 MMP1 (1.00) MMP1MMP3MMP8MMP9MMP7
SCHEMBL7408812 0.88 MMP1 (0.79) MMP1MMP3MMP8MMP9MMP7
SCHEMBL7409487 0.88 MMP1 (0.79) MMP1MMP3MMP8MMP9MMP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0925303-B1 PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS PROCTER & GAMBLE (US) 2002-10-23 — — EP disclosed