Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450305 | 0.81 | BRD4 (0.39) | BRD4CREBBP | |
| SCHEMBL7371836 | 0.73 | PNP (0.33) | BRD4CREBBPSLC6A4 | |
| SCHEMBL12441883 | 0.62 | PLK1 (0.72) | — | |
| SCHEMBL21060861 | 0.58 | PPARA (0.41) | MPO | |
| SCHEMBL2575471 | 0.57 | ALDH1A1 (0.46) | — | |
| SCHEMBL21192538 | 0.56 | GAA (0.56) | BRD4 | |
| SCHEMBL11774693 | 0.56 | BRD4 (0.35) | BRD4CREBBP | |
| SCHEMBL6642225 | 0.56 | PADI4 (0.32) | — | |
| SCHEMBL3960641 | 0.55 | GLA (0.37) | BRD4CREBBP | |
| SCHEMBL8338794 | 0.55 | GAA (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257553-A1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK Chemicals Co., Ltd. (KR) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001060825-A1 | PYRROLOPYRIMIDINONE DERIVATIVES, PROCESS OF PREPARATION AND USE | SK CHEMICALS CO., LTD. (KR) | 2001-08-23 | — | — | WO | disclosed |