Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 7/20 | 0.51 |
| ▸ | CTSS | P25774 | 7/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | YAP1 | P46937 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370096 | 0.88 | TACR2 (0.60) | TACR2 | |
| SCHEMBL7408901 | 0.87 | TACR2 (0.54) | TACR2CTSSYAP1 | |
| SCHEMBL7367334 | 0.85 | CACNA1B (0.54) | TACR2CTSSYAP1PTPN1 | |
| SCHEMBL8207767 | 0.83 | REN (0.48) | TACR2CTSSCTSKCTSLYAP1 | |
| SCHEMBL7368981 | 0.83 | CACNA1B (0.58) | TACR2CTSSCTSK | |
| SCHEMBL7402583 | 0.83 | TACR2 (0.54) | TACR2CTSSCTSK | |
| SCHEMBL7371474 | 0.83 | YAP1 (0.53) | CTSSCTSKCTSLYAP1PTPN1 | |
| SCHEMBL7371480 | 0.83 | YAP1 (0.53) | CTSSCTSKCTSLYAP1PTPN1 | |
| SCHEMBL8194350 | 0.83 | IL1RN (0.48) | TACR2CTSSCTSKCTSLYAP1 | |
| SCHEMBL7371242 | 0.83 | CACNA1B (0.61) | CTSSYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117841-A | USED TO TREAT STROKE, CEREBRAL ISCHEMIA, PAIN, HEAD TRAUMA OR EPILEPSY | WARNER-LAMBERT COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| WO-1998054123-A1 | SUBSTITUTED PEPTIDYLAMINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1998-12-03 | — | — | WO | disclosed |