Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.38 |
| ▸ | ITGAV | P06756 | 17/20 | 0.38 |
| ▸ | ITGB6 | P18564 | 12/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.33 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.33 |
| ▸ | ITGA8 | P53708 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346981 | 0.81 | SMN1; SMN2 (0.39) | ITGB3ITGAVITGB6ITGA2BLMNA | |
| SCHEMBL7450003 | 0.81 | ITGB3 (0.60) | ITGB3ITGAVITGB6ITGA2BITGB1 | |
| SCHEMBL7375174 | 0.73 | ITGB3 (0.33) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL7449770 | 0.73 | ITGB3 (0.59) | ITGB3ITGAVITGB6ITGA2BITGB1 | |
| SCHEMBL6777825 | 0.73 | ITGB3 (0.68) | ITGB3ITGAVITGB6ITGA2BITGB1 | |
| SCHEMBL6780815 | 0.72 | ITGB3 (0.67) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL7340034 | 0.70 | LMNA (0.38) | ITGB3ITGAVITGB6ITGA2BLMNA | |
| SCHEMBL7345081 | 0.69 | ITGB3 (0.40) | ITGB3ITGAVITGB6ITGA2BLMNA | |
| SCHEMBL7347208 | 0.69 | SMN1; SMN2 (0.41) | ITGB3ITGAVITGA2BLMNASMN1; SMN2 | |
| SCHEMBL7345093 | 0.68 | HTT (0.39) | ITGB3ITGAVITGB6ITGA2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |