Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.33 |
| ▸ | ITGAV | P06756 | 17/20 | 0.33 |
| ▸ | ITGB6 | P18564 | 12/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346229 | 0.82 | ITGB3 (0.36) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL7346234 | 0.82 | KMT2A (0.34) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL7367982 | 0.73 | ITGB3 (0.38) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL7336943 | 0.73 | NPC1 (0.33) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL6777825 | 0.67 | ITGB3 (0.68) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL6780815 | 0.67 | ITGB3 (0.67) | ITGB3ITGAVITGB6 | |
| SCHEMBL7340943 | 0.66 | ITGB1 (0.34) | ITGB3ITGAVITGA2B | |
| SCHEMBL7340934 | 0.65 | ITGB3 (0.37) | ITGB3ITGAVITGA2B | |
| SCHEMBL7345255 | 0.64 | ITGB3 (0.53) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL7346389 | 0.63 | MAPT (0.35) | ITGB3ITGAVITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997008145-A1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1997-03-06 | — | — | WO | claimed |