Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089327 | 0.78 | CHRNA7 (0.64) | CHRNA7HTR3AYTHDC1FLT3CNR1 | |
| SCHEMBL2087087 | 0.76 | DYRK1A (0.48) | CHRNA7HTR3AYTHDC1FLT3NPC1 | |
| SCHEMBL7368125 | 0.75 | SMN1; SMN2 (0.51) | CHRNA7HTR3AYTHDC1CNR1CNR2 | |
| SCHEMBL3695594 | 0.75 | DYRK1A (0.46) | CHRNA7HTR3AYTHDC1FLT3NPC1 | |
| Hydrochloric Acid SCHEMBL6411553 | 0.74 | DYRK1A (0.46) | CHRNA7HTR3AYTHDC1FLT3NPC1 | |
| SCHEMBL12441910 | 0.72 | CHRNA7 (0.64) | CHRNA7HTR3AYTHDC1FLT3CNR1 | |
| SCHEMBL2086156 | 0.72 | CHRNA7 (0.64) | CHRNA7HTR3AYTHDC1FLT3CNR1 | |
| SCHEMBL1176568 | 0.71 | YTHDC1 (0.49) | CHRNA7HTR3AYTHDC1FLT3CNR1 | |
| SCHEMBL2013744 | 0.71 | KDM4E (0.46) | CHRNA7HTR3AYTHDC1FLT3CNR1 | |
| SCHEMBL5038866 | 0.71 | YTHDC1 (0.49) | CHRNA7HTR3AYTHDC1FLT3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200444-A2 | Azabicyclononyl-indazole-carboxamide having 5-HT antagonist activity | BEECHAM GROUP PLC (GB) | 1986-11-05 | — | — | EP | claimed |