Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 3/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591375 | 0.97 | SLC15A1 (0.43) | TAAR1SLC15A1ALPIPKMPTGS1 | |
| SCHEMBL10590665 | 0.86 | CYP3A4 (0.47) | SLC15A1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL7360306 | 0.84 | SLC15A1 (0.47) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7361302 | 0.83 | CYP1A2 (0.47) | SLC15A1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL7359102 | 0.77 | CYP1A2 (0.52) | SLC15A1LAP3ANPEPRNPEPDNPEP | |
| SCHEMBL7357671 | 0.77 | SLC15A1 (0.44) | TAAR1SLC15A1ALPIPKMPTGS1 | |
| SCHEMBL6580113 | 0.77 | SLC15A1 (0.44) | TAAR1SLC15A1ALPIPKMPTGS1 | |
| SCHEMBL11998010 | 0.77 | SLC15A1 (0.44) | TAAR1SLC15A1ALPIPKMPTGS1 | |
| SCHEMBL11998023 | 0.77 | SLC15A1 (0.44) | TAAR1SLC15A1ALPIPKMPTGS1 | |
| SCHEMBL10871667 | 0.76 | EPHX2 (0.45) | TAAR1SLC15A1ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |