Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591375 | 0.84 | SLC15A1 (0.43) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7368172 | 0.84 | TAAR1 (0.44) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7359102 | 0.78 | CYP1A2 (0.52) | SLC15A1CYP1A2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7358486 | 0.72 | CYP1A2 (0.43) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL7357671 | 0.71 | SLC15A1 (0.44) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL11998023 | 0.71 | SLC15A1 (0.44) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL11998010 | 0.71 | SLC15A1 (0.44) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL6580113 | 0.71 | SLC15A1 (0.44) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7946886 | 0.71 | TACR1 (0.41) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL10871667 | 0.70 | EPHX2 (0.45) | SLC15A1ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415981-A4 | RETROVIRAL PROTEASE INHIBITORS | — | 1991-10-09 | — | — | EP | disclosed |
| EP-0415981-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989010752-A1 | RETROVIRAL PROTEASE INHIBITORS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |