Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | BCR | P11274 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369784 | 0.86 | IMPDH2 (0.37) | MAP2K4RAB9AGABRA1GABRG2GABRB3 | |
| SCHEMBL12491369 | 0.79 | MAP2K4 (0.61) | MAP2K4RAB9APARP1DYRK1AKIF11 | |
| SCHEMBL8890934 | 0.74 | PRKAB2 (0.50) | MAP2K4GSK3BDYRK1APRKAB2PRKAG1 | |
| SCHEMBL23675227 | 0.68 | MAP2K4 (0.54) | MAP2K4RAB9AKIF11JAK2NPC1 | |
| SCHEMBL29564826 | 0.68 | MAP2K4 (0.54) | MAP2K4RAB9AKIF11JAK2NPC1 | |
| SCHEMBL27819729 | 0.68 | ELANE (0.45) | GABRA1GABRG2GABRB3PRKAB2PRKAG1 | |
| SCHEMBL7373521 | 0.68 | ALDH1A1 (0.46) | JAK2 | |
| SCHEMBL7368266 | 0.68 | CA12 (0.47) | GSK3BJAK2SRC | |
| SCHEMBL4404846 | 0.66 | MAP2K4 (0.56) | MAP2K4RAB9APARP1ABL1BCR | |
| SCHEMBL30159687 | 0.66 | MAP2K4 (0.56) | MAP2K4RAB9APARP1ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019045-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1019045-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999000128-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |